they normally widen the puncture holes first before adding the rear mushroom. not sure of the limit of size or if the rubber has torn around the puncture in which case you’re screwed (exuse the pun)
whichever garage is gonna switch the tyre for you will be able to tell you if its plug or replace. doubt they see many with bolts through 'em tho!
never had a plug go…had them fitted in all sorts of puncture holes, in a tear in a hole bigger that that and still fine…they are very very good…but as with all things these days H&S will say it is unpluggable, get a kit and do it yourself and see if it is or not…bet it is…